Description
What it is
GHK-Cu is a naturally occurring copper-binding tripeptide
composed of three amino acids (glycine, histidine, lysine) complexed to a copper ion. It occurs
endogenously in mammalian plasma, saliva and urine, and its concentration is reported to decline
with age — one reason it has attracted sustained research interest.
The sections below summarise findings reported in published preclinical and early-stage literature. They describe what has been observed in study models, not outcomes offered to any purchaser.
Areas of Research Interest
1. Collagen synthesis and extracellular matrix
- Studied for stimulation of collagen and elastin synthesis in fibroblast cultures
- Investigated for its relationship to dermal matrix density and structural protein turnover
- Examined for effects on melanin-related pathways in pigmentation models
2. Wound-healing and inflammatory signalling
- Investigated in preclinical wound models for tissue-repair signalling
- Studied for modulation of inflammatory mediators
- Examined for its role in angiogenesis (formation of new blood vessels)
3. Follicular research models
- Studied for effects on hair-follicle activity in animal and cell-culture models
- Investigated for its influence on the follicular growth cycle
4. Gene expression and cellular turnover
- Reported to influence expression of genes associated with repair and remodelling
- Studied in relation to clearance of damaged proteins
- Investigated for antioxidant activity linked to copper coordination
References
- Pickart L, Margolina A. Int J Mol Sci, 2018;19(7):1987
- Pickart L et al., Biochim Biophys Acta, 2015;1850(8):1863–1885
- Gruchlik A et al., Acta Pol Pharm, 2012;69(6):1303–1306
Handling and Storage
Lyophilised powder. Store the sealed vial refrigerated and protected from light. To be handled
only by trained laboratory personnel in an appropriate research setting.
Research Use Only
This product is sold exclusively as a research chemical for in-vitro laboratory investigation by qualified researchers. It is not a drug, not a dietary supplement, and not intended for human or veterinary consumption, diagnostic use, or any form of therapeutic application. No statement on this page should be read as medical advice or as a claim that this compound treats, prevents, or cures any condition. Findings referenced above are drawn from published preclinical and clinical literature and are provided for scientific reference only.

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