Melanotan 2 (10mg)

$50.00

Melanotan 2 is a synthetic cyclic heptapeptide and nonselective melanocortin receptor agonist used in receptor binding and MC1R-MC5R signal transduction studies. Supplied as a 10 mg vial for laboratory research use only.

Description

Melanotan 2 is a synthetic cyclic heptapeptide (Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂) that functions as a potent nonselective melanocortin receptor agonist. It is employed in receptor binding and signal transduction studies exploring MC1R–MC5R-mediated cAMP activation and GPCR desensitization mechanisms. MT-II provides a research model for peptide–receptor pharmacology and neuroendocrine signaling dynamics. What is Melanotan 2 (MT-2)?Melanotan 2 (MT-2) is a synthetic version of human alpha-melanocyte-stimulating hormone (α-MSH). It was originally developed in the 1980’s, at the University of Arizona, after it was found that α-MSH caused sexual arousal in rodents as well as darkening of the skin. Originally as a sunless tanning option. MT-2 was eventually found to have a wide range of effects such as in:increasing sexual arousalpromoting tanning or skin pigmentationreducing compulsive behaviorcontrolling addictionfighting hungerreducing glucagon productionreversing features of autism Reference Citationshttps://www.ncbi.nlm.nih.gov/pubmed/30629642https://www.ncbi.nlm.nih.gov/pubmed/26312834https://www.researchgate.net/publication/24019710_The_Role_of_Leptin-Melanocortin_System_and_Human_Weight_Regulation_Lessons_from_Experiments_of_Naturehttps://www.ncbi.nlm.nih.gov/pubmed/12481551https://www.ncbi.nlm.nih.gov/pubmed/14764630https://www.ncbi.nlm.nih.gov/pubmed/27115412https://www.ncbi.nlm.nih.gov/pubmed/19752162https://www.ncbi.nlm.nih.gov/pubmed/21167196https://www.ncbi.nlm.nih.gov/pubmed/26108334https://www.ncbi.nlm.nih.gov/pubmed/9679884https://doi.org/10.1111/j.1749-6632.2003.tb03166.xhttps://www.nature.com/articles/3900371.pdfhttps://pubmed.ncbi.nlm.nih.gov/35907397/https://pubmed.ncbi.nlm.nih.gov/33623128/

Research Use Only
This product is sold exclusively as a research chemical for in-vitro laboratory investigation by qualified researchers. It is not a drug, not a dietary supplement, and not intended for human or veterinary consumption, diagnostic use, or any form of therapeutic application. No statement on this page should be read as medical advice or as a claim that this compound treats, prevents, or cures any condition. Findings referenced above are drawn from published preclinical and clinical literature and are provided for scientific reference only.

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